UK Regulatory Agency Warns Against Melanotan Purchased on the Internet

The United Kingdom’s Medicines and Healthcare products Regulatory Agency has warned against using Melanotan purchased on the Internet. I’ve written about Melanotan before — it is a drug that tans the skin, increases the libido, and suppresses appetite. It has been in testing for the better part of a decade, but is still not approved for sale in the United States or Europe.

This hasn’t stopped US-based Melanocorp from selling the drug just the same. In 2007, the U.S. Food and Drug Administration issued a warning letter to Melanocorp to stop selling melanotan in the United States,

Melanocorp, Inc. advertises the product Melanotan II on its Web site as an injectable tanning product, with additional claims that it is effective in protecting against skin cancer and rosacea (a flushing and redness of the skin). These claims cause Melanotan II to be classified as a drug under the Federal Food, Drug and Cosmetic Act, as well as a new drug because there is no evidence that it is generally recognized as safe and effective for its labeled uses. This product does not have an approved new drug application. The product’s introduction and delivery into interstate commerce, therefore, violates federal law. The risks run by patients who use unapproved new drugs could include adverse side effects from inappropriately prescribed medications, dangerous drug interactions, and harm from contaminated, counterfeit or outdated drugs. The FDA cautions consumers about injecting any substance, particularly products that are not FDA-approved, into their bodies without the oversight of a licensed health care provider.

Issuance of this Warning Letter is consistent with FDA’s focus on fraudulent products marketed on the Internet for serious and life-threatening diseases. Individuals and firms that do not resolve violations of the Federal Food, Drug, and Cosmetic Act risk injunction to halt the illegal activities, seizure of violative products, and other regulatory sanctions.

Melanocorp stopped taking orders for Melanotan in the U.S. shortly afterward, but apparently still sells to consumers in other countries. According to The Guardian, there are at least 18 companies that sell Melanotan on the Internet.

Better Living Through Provigil?

A couple years ago I mentioned up-and-coming lifestyle drugs melanotan and provigil. Salon.Com’s Larry Smith sampled some provigil, but unfortunately his experience with the drug was not good.

Provigil is billed as an drug to keep people awake without the nasty side effects attendant with commonly used stimulations. Smith, however, found the drug similar to cocaine and aborted his usage of the drug after a few days.

It’d be interesting to see how someone without the extensive recreational drug use history that Smith apparently has would handle the drug.

The other problem at the moment is cost. Even if you’ve got a really good health insurance plan, it’s not going to cover provigil for recreational use and a month’s supply is going to set you back $250 or so.

The other lifestyle drug I mentioned, melanotan, tans the skin, increases sexual desire and suppresses appetite. Unfortunately, its still in pre-clinical testing as far as I can tell.

Source:

Better waking through chemistry. Larry Smith, Salon.Com, November 12, 2004.

Better Living Through Chemistry: Bring On Melanotan and Provigil

Some people just can’t stand seeing other people happy — especially if that happiness is “unnatural.”

In Wired, for example, Wil McCarthy takes on the wonder drug Melanotan. Melanotan has chemical properties that sound like a pharmaceutical marketer’s dream come true. The drug’s major effect is to create a deep, healthy tan. And it also just happens to be an anti-inflammatory, increases sexual desire and suppresses appetite.

McCarthy derisively refers to Melanotan as “the Barbie drug.” He concludes his noting that by the end of this decade Melanotan and drugs like it will be common adding that, “this decade is a breathing period, a chance to prepare for our cultural destiny: the drug-fueled extreming an professionalization of shallowness itself.”

For McCarthy, using chemical compounds to increase the sheer joy of life is inherently shallow and a waste. To McCarthy, drugs like Melanotan are proof that “Yesterday’s drugs were about need; today’s are about desire.”

Much the same criticism was directed against Viagra when it first appeared. A drug to produce erections? Aren’t children still dying of malaria in Africa? Who needs Viagra?

Similar handwringing was on display over Provigil. Provigil has been used for years to treat narcolepsy. The drug’s maker wants the FDA to approve Provigil for more widespread use.

Provigil doesn’t increase sexual desire, but it does act as a stimulant to keep people awake — with very little side effects. Stimulants commonly used by people to stay awake tend to make people jittery or are addictive and all tend to keep a person awake for hours only to bring him or her crashing down later.

In studies Provigil keeps people awake for long periods without the jitters, addictiveness, and other problems associated with other stimulants.

The major concern about Provigil is that it may be abused, but certainly caffeine and other stimulants are already used excessively by many people.

Personally, I’d love to get my hands on either drug. Why should not used drugs not only to treat/cure disease, but also to improve our general well being? These sorts of drugs need to be safe and have potential side effects disclosed, but I would hope that once those criteria are met that we would not slip into McCarthy’s brand of biomedical Puritanism that sees the pursuit of joy and happiness as inherently shallow.

Sources:

Thin! Tan! Hotter than Hell! Wil McCarthy, Wired, June 2002.

Stay-awake pill keeps users alert. Dan Springer, Fox News, May 2, 2002.